Menthol, (+/-)

  • Racementhol
  • methylhydroxyisopropylcyclohexane
Formula
C10H20O
Structure
Description
White solid.
Uses
Has local anesthetic and counterirritant qualities

Registry Numbers and Inventories.
CAS
15356-70-4
EC (EINECS/ELINCS)
239-388-3
RTECS
OT0525000
RTECS class
Tumorigen; Mutagen; Primary Irritant
Beilstein/Gmelin
3194263
Beilstein Reference
4-06-00-00151
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C10H20O
Formula mass
156.26
Melting point, °C
30 - 32
Boiling point, °C
216
Vapor pressure, mmHg
0.03 (25 C)
Density
0.9 g/cm3 (15 C)
Solubility in water
Insoluble
Refractive index
1.4615 (20 C)
Partition coefficient, pKow
3.20
Heat of fusion
10.3 kJ/mol
Heat of vaporization
52.5 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizers.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
91
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May cause allergic reactions
   Inhalation
May cause respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
May cause severe eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
20. Alcohols. Glycols