- Methyl isobutenyl ketone
Colorless to yellow oily liquid, peppermint- like odor. Lachrymator.
Solvent for nitrocellulose, many gums & resins, particularly vinyl resins, in lacquers, varnishes & enamels. Extractant of trace amounts of copper(II).
Registry Numbers and Inventories.
EC Index Number
R 10 20/21/22
Human Data; Primary Irritant
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
8.8 (25 C)
Vapor density (air=1)
1.1% at 20 C
8.4 (Butyl acetate = 1)
Odor Threshold Odor threshold 0.068 mg/m3
Solubility in water
28.9 g/L (20 C)
0.88 cp (25 C)
27.12 g/s2 (24 C)
1.4425 (20 C)
15.6 (0 C)
Partition coefficient, pKow
Heat of vaporization
Heat of combustion
Hazards and Protection.
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition. Use a spark-proof tool. Isolate area and deny entry. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Stable under normal temperatures and pressures.
2-Aminoethanol, strong oxidizing agents, chlorosulfonic acid, ethylene diamine, nitric acid, oleum, sulfuric acid.
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Upper exp. limit, %
Lower exp. limit, %
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use water spray to cool fire-exposed containers. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water.
Flammable liquid and vapor.
Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back. Containers may explode in the heat of a fire.
Combustion may produce irritants and toxic gases.
NIOSH REL: TWA 10 ppm (40 mg/m3) OSHA PEL: TWA 25 ppm (100 mg/m3) 1400 ppm [10%LEL]
Prolonged or repeated inhalation may cause lung damage and/or central nervous system disturbances. Prolonged or repeated skin contact may cause dermatitis. May cause liver and kidney damage.
May cause irritation of the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May be harmful if swallowed. Ingestion of large amounts may cause CNS depression.
Causes respiratory tract irritation. May cause liver and kidney damage. May cause lung damage. Causes narcotic effects including headache, dizziness, weakness, unconsciousness, and possible death. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause burning sensation in the chest.
May cause severe skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis. Substance is rapidly absorbed through the skin. May cause irritation and dermatitis. May cause cyanosis of the extremities.
Causes severe eye irritation. Vapors may cause eye irritation. May cause corneal opacity as in addition to corneal scarring and necrosis. May cause chemical conjunctivitis and corneal damage.
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.