Methacryloyloxyethyl isocyanate

  • 2-Isocyanatoethyl methacrylate
  • 2-(Methacryloyloxy)ethyl isocyanate
  • Methacrylic acid, 2-isocyanatoethyl ester
  • 2-Propenoic acid, 2-methyl-, 2-isocyanatoethyl ester
  • Isocyanic acid, 2-hydroxyethyl ester methacrylate (ester)
Formula
C7H9NO3
Structure

Registry Numbers and Inventories.
CAS
30674-80-7
EC (EINECS/ELINCS)
250-284-7
RTECS
OZ4950000
RTECS class
Reproductive Effector
UN (DOT)
3080
Beilstein/Gmelin
1768533
Beilstein Reference
4-04-00-01555
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H9NO3
Formula mass
155.17
Boiling point, °C
219
Vapor pressure, mmHg
0.12 (25 C)
Critical temperature
390
Critical pressure
28.5
Solubility in water
Insoluble
Refractive index
1.4496 (20 C)
Partition coefficient, pKow
2.27
Heat of vaporization
45.5 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
(Non-Specific -- Isocyanates and Solutions, n.o.s. (Flammable, Poisonous)) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Shut off ignition sources; no flares, smoking or flames in hazard area. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal.
Stability
No data.
Incompatibilities
Incompatible with many classes of compounds, reacting exothermically to release toxic gases Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat.

Fire.
Flash Point,°C
93
Fire fighting
(Non-Specific -- Isocyanates and Solutions, n.o.s. (Flammable, Poisonous)) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Move container from fire area if you can do it without risk. Cool containers that are exposed to flames with water from the side until well after fire is out. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.(Non-Specific -- Isocyanates and solutions, n.o.s. (Flammable, Poisonous)) Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
   Ingestion
Inhalation of vapor or aerosol may produce vomiting and abdominal pain. Epigastric and substernal pain may be secondary to the paroxysmal or persistent cough associated with inhalation.
   Inhalation
Burning or irritation of the nose and throat, cough, laryngitis, chest pain, and asthmatic syndrome (chemical bronchitis with severe bronchospasm) sensation of oppression or constriction of the chest, bronchitis, emphysema and cor pulmonale may occur.
   Skin
Irritation and inflammation are common with isocyanates. Isocyanates may burn the skin.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Due to the irritant nature of isocyanates, vomiting is not advised. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Monitor patient for respiratory distress. If a cough or difficulty in breathing develops, evaluate for respiratory tract irritation, bronchitis and pneumonia. Allergic reaction - sensitized individuals should be cautioned to avoid further exposure, as serious allergic reactions may result.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
3080
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
MAI