Methanesulfonyl chloride

  • Methanesulfonic acid chloride
  • Methylsulfonyl chloride
  • Mesyl chloride
Formula
CH3SO2Cl
Structure
Description
Pale yellow liquid.
Uses
Intermediate, flame-resistant products, stabilizer for liquid sulfur trioxide, biological chemicals.

Registry Numbers and Inventories.
CAS
124-63-0
EC (EINECS/ELINCS)
204-706-1
EC Class
very toxic, corrosive, dangerous for the environment
R 26 21/22 35 37
S 26 36/37/39 45
RTECS
PB2790000
RTECS class
Mutagen; Primary Irritant
UN (DOT)
3246
Merck
13,5982
Beilstein/Gmelin
506297
Beilstein Reference
4-04-00-00027
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
CH3ClO2S
Formula mass
114.55
Melting point, °C
-32
Boiling point, °C
161
Vapor pressure, mmHg
3 (25 C)
Vapor density (air=1)
4
Density
1.48053 g/cm3 (18 C)
Solubility in water
Soluble
Refractive index
1.451 (20 C)
Partition coefficient, pKow
0.24
Heat of vaporization
48.15 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container. Corrosives area.
Handling
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Disposal code
11
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Water - strong bases - oxidizing agents - alcohols.
Decomposition
Hydrogen chloride, carbon monoxide, oxides of sulfur, carbon dioxide.

Fire.
Flash Point,°C
42
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Do NOT use water directly on fire. Use carbon dioxide or dry chemical.
Fire potential
May burn but does not ignite readily.
Hazards
Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
2 (Very strong toxins)
Exposure effects
   Ingestion
Causes gastrointestinal tract burns.
   Inhalation
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
   Skin
Causes skin burns.
   Eyes
Causes eye burns. Lachrymator.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Treat symptomatically and supportively.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3246
Response guide
Hazard class
6.1
PRTC
T
Packing Group
I
 
HS Code
2904 90 20
 
Std. Transport #
4921245