Methapyrilene hydrochloride

  • 2-((2-(Dimethylamino)ethyl)-2-thenylamino)pyridine monohydrochloride
Formula
C14H19N3S.HCl
Structure
Description
White crystalline powder or solid with a faint odor. Bitter taste.

Registry Numbers and Inventories.
CAS
135-23-9
EC (EINECS/ELINCS)
205-184-8
RTECS
UT1750000
RTECS class
Tumorigen; Drug; Mutagen; Human Data
Beilstein/Gmelin
6099172
Beilstein Reference
4-22-00-03950
EPA OPP
97006
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C14H19N3S*ClH
Formula mass
297.84
Melting point, °C
164.5 - 166.5
Density
1.236 g/cm3

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents Reactions with these materials generate heat and in many cases hydrogen gas.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is probably combustible.

Health.
Exposure effects
   Ingestion
See inhalation.
   Inhalation
Symptoms of exposure to this compound include gastritis. Other symptoms include excitement, convulsions, hyperpyrexia, cerebral edema, depression and renal tubular necrosis. Ingestion of this type of compound may cause drowsiness, headache, dryness of the mouth, nausea, tachycardia, urinary retention, disorientation, nervousness, staggering gait, hallucinations, stupor, coma, hyperreflexia, tremors, nystagmus and hyperthermia. Other symptoms of exposure to this type of compound are mild sedation, inability to concentrate, lassitude, dizziness, hypotension, muscular weakness, incoordination, vomiting, diarrhea or constipation, epigastric pain, blurred vision and tinnitus.
   Skin
See inhalation.
   Eyes
See inhalation

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.