Methyl 3-aminocrotonoate

  • beta-Aminocrotonic acid methyl ester
  • 3-Aminocrotonic acid methyl ester
  • Crotonic acid, 3-amino-, methyl ester
  • Methyl 3-amino-2-butenoate
  • Methyl beta-aminocrotonate
Formula
CH3C(NH2)=CHCOOCH3
Structure
Description
White crystalline powder.

Registry Numbers and Inventories.
CAS
14205-39-1
EC (EINECS/ELINCS)
238-056-5
R 22 36
S 26 36/37/39
RTECS
EM9092500
RTECS class
Primary Irritant
Beilstein/Gmelin
956592
Beilstein Reference
2-03-00-00414
Swiss Giftliste 1
G-8497
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C5H9NO2
Formula mass
115.13
Melting point, °C
83 - 84
Boiling point, °C
194
Vapor pressure, mmHg
0.45 (25 C)
Vapor density (air=1)
4.0
Solubility in water
Very soluble
pKa/pKb
7.74 (pKb)
Partition coefficient, pKow
-0.14
Heat of vaporization
43.0 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
91
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Health.
Poison_Class
4
Exposure effects
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2922 49 95