Methyl acetate

  • Acetic acid, methyl ester
  • Methyl ethanoate
  • Methyl acetic ester
Formula
CH3COOCH3
Structure
Description
Colorless, volatile liquid, pleasant, fruity odor.
Uses
Solvent for nitrocellulose, acetylcellulose, resins & oils, manufacture artificial leather.

Registry Numbers and Inventories.
CAS
79-20-9
EC (EINECS/ELINCS)
201-185-2
EC Index Number
607-021-00-X
EC Class
Highly flammable; Irritant; Repeated exposure may cause skin dryness or cracking; Vapours may cause drowsiness and dizziness
R 11 36 66 67
S 16 26 29 33
RTECS
AI9100000
RTECS class
Mutagen; Human Data; Primary Irritant
UN (DOT)
1231
Merck
12,6089
Beilstein/Gmelin
1736662
Beilstein Reference
4-02-00-00122
Swiss Giftliste 1
G-2418
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H6O2
Formula mass
74.08
Melting point, °C
-98
Boiling point, °C
56.9
Vapor pressure, mmHg
171 (20 C)
Vapor density (air=1)
2.6
Saturation Concentration
22.77% at 20 C
Evaporization number
2.2 (diethyl ether = 1)
Odor Threshold Odor threshold 3.0 mg/L
Critical temperature
233.7
Critical pressure
45.3
Density
0.938 g/cm3 (20 C)
Solubility in water
320 g/L (20 C)
Viscosity
0.385 cp (20 C)
Surface tension
24.8 g/s2 (20 C)
Refractive index
1.3614 (20 C)
Dipole moment
1.706 D
Dielectric constant
6.6 (25 C)
Partition coefficient, pKow
0.18
Heat of vaporization
32.5 kJ/mol
Heat of combustion
-1672 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances.
B2 D2B
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite.
Disposal code
1
Stability
Stable at room temperature in sealed containers under normal storage and handling conditions.
Incompatibilities
Nitrates, strong oxidizers, alkalis, and acids. Reacts slowly with water to form acetic acid and methanol.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
-13
Autoignition, °C
455
Upper exp. limit, %
16 .0
Lower exp. limit, %
3.1
Fire fighting
Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Extinguish using dry chemical, alcohol foam or carbon dioxide. Water may be ineffective. Water spray may be used to keep fire exposed containers cool. Water may be used to flush spills away from exposures and to dilute spills to non-flammable mixtures.
Fire potential
Flammable liquid and vapor.
Hazards
Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA PEL: TWA 200 ppm (610 mg/m3) NIOSH REL: TWA 200 ppm (610 mg/m3) ST 250 ppm (760 mg/m3) NIOSH IDLH: 3100 ppm LEL
Poison_Class
3
Exposure effects
Repeated contact with the liquid may cause dryness, cracking, and skin irritation. Causes eye irritation. Affects the central nervous system. Chronic effects may be similar to those from methanol exposure because methyl acetate can be hydrolyzed yielding methanol and acetic acid. Optic nerve damage is the predominant hazard.
   Ingestion
May produce abdominal pain, nausea. Aspiration into lungs can produce severe lung damage and is a medical emergency. Other symptoms expected to parallel inhalation.
   Inhalation
Inhalation of vapors causes irritation to the eyes, nose, and respiratory tract. Vapors have a narcotic effect, producing symptoms of dizziness, depression, shortness of breath, and irregular heartbeat. High concentrations can cause CNS depression characterized by eye inflammation, nervous irritation, chest tightness, headache, dizziness, drowsiness, difficulty breathing, palpitation, and conjunctivitis.
   Skin
Causes loss of natural oils and skin irritation.
   Eyes
Vapors can cause irritation with redness, tearing, and pain. A severe irritant to the eyes from liquid splashes.

First aid
 
   Ingestion
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT INDUCE. If vomiting occurs, keep head below hips to prevent aspiration into lungs. Never give anything by mouth to an unconscious person. Call a physician immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1231
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
MTT
 
HS Code
2915 39 30
 
Std. Transport #
4908220
 
IMO Chemical Code
18
IMO Pollution Category
III