Methyl amyl acetate

  • 4-Methyl-2-amyl acetate
Formula
C8H16O2
Structure
Description
A clear colorless liquid.
Uses
As fragrances in the perfume and cosmetics industry, as components for housefly insecticides, and as chemical components for the large spruce bark beetle attractant. Hexyl acetates.

Registry Numbers and Inventories.
CAS
108-84-9
EC (EINECS/ELINCS)
203-621-7
RTECS
SA7525000
RTECS class
Human Data; Primary Irritant
UN (DOT)
1233
Beilstein/Gmelin
1749848
Beilstein Reference
4-02-00-00161
Swiss Giftliste 1
G-1687
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H16O2
Formula mass
144.24
Melting point, °C
-63.8
Boiling point, °C
141
Vapor pressure, mmHg
5.1 (25 C)
Vapor density (air=1)
5.0
Critical temperature
319
Critical pressure
26
Density
0.8805 g/cm3 (0 C)
Solubility in water
0.8 g/L
Surface tension
25 g/s2
Refractive index
1.4118 (18 C)
Partition coefficient, pKow
2.47
Heat of vaporization
38.2 kJ/mol
Heat of combustion
-2442 kJ/mol

Hazards and Protection.
Storage
Store in a cool place, away from sources of ignition.
B3
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning. Organic canister or air pack; rubber gloves, goggles. Wear appropriate eye protection and protective clothing to prevent skin and eye contact.
Respirators
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure mode.
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Stability
Stable.
Incompatibilities
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products Incompatible with the following: Nitrates; strong oxidizers, alkalis & acids.

Fire.
Flash Point,°C
38
Autoignition, °C
265
Lower exp. limit, %
0.9
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Toxic gases and vapors (such as carbon monoxide) may be released in a fire involving sec-hexyl acetate.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
NIOSH REL: TWA 50 ppm (300 mg/m3) OSHA PEL: TWA 50 ppm (300 mg/m3) IDLH 500 ppm
Poison_Class
5
Exposure effects
   Ingestion
Nausea, vomiting and diarrhea are possible if ingested.
   Inhalation
Cough, tachypnea, and wheezing are common after inhalation.
   Skin
Redness, swelling and pain may occur.
   Eyes
Irritants may cause swelling, redness and pain at any site, especially at mucous membranes. The mouth, nose, and eyes are susceptible to these effects.

First aid
 
   Ingestion
Emesis is not indicated due to the irritant nature of these agents. Charcoal - not recommended; it may promote vomiting and make endoscopic evaluation difficult. Dilution: immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 4 ounces/120 ml in a child). Neutralization - neutralization is not indicated. Although these agents are irritants, and therefore should not produce tissue damage, it is almost impossible to assure that a particular substance under a particular set of circumstances would not cause damage. Therefore, each patient should be examined with the idea that mucous membrane damage might have occurred.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove and isolate contaminated clothing and shoes. Wash skin with soap and water. Flush with running water for at least 20 minutes
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. If in a medical facility, sterile saline should be used to irrigate the eyes until the cul de sac is returned to neutrality. Some alkali exposures may require prolonged irrigation.

Transport.
UN number
1233
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
MAC
 
Std. Transport #
4909235
 
IMO Pollution Category
C
IMO Hazard code
P