Methyl chloroacetate

  • Chloroacetic acid, methyl ester
Formula
ClCH2COOCH3
Structure
Description
A crystalline solid or a solid dissolved in a liquid.
Uses
Solvent, intermediate.

Registry Numbers and Inventories.
CAS
96-34-4
EC (EINECS/ELINCS)
202-501-1
EC Index Number
607-205-00-X
EC Class
Flammable; Toxic; Irritant
R 10 23/25 37/38 41
S 26 37/39 45
RTECS
AF9500000
RTECS class
Other
UN (DOT)
2295
Merck
12,6122
Beilstein/Gmelin
506255
Beilstein Reference
4-02-00-00480
Swiss Giftliste 1
G-2017
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H5ClO2
Formula mass
108.53
Melting point, °C
-33
Boiling point, °C
131
Vapor pressure, mmHg
8 (20 C)
Vapor density (air=1)
1.24
Evaporization number
0.35 (20 C) (diethyl ether = 1)
Critical temperature
327
Critical pressure
44.4
Density
1.2378 g/cm3 (20 C)
Solubility in water
28 g/L
Viscosity
1.143 cp (20 C)
Surface tension
35.2 g/s2 (20 C)
Refractive index
1.4218 (20 C)
Partition coefficient, pKow
0.41
Heat of vaporization
49.9 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Handling
Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Disposal code
9
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong acids, strong bases, strong oxidizing agents, strong reducing agents.
Decomposition
Hydrogen chloride, phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
52
Autoignition, °C
465
Upper exp. limit, %
18.5
Lower exp. limit, %
4.6
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Contact with metals may evolve flammable hydrogen gas. Extinguishing media: For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT get water inside containers. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam.
Fire potential
Flammable when exposed to heat or flame.
Hazards
Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
Combustion products
Toxic fumes of hydrogen chloride
Health
2
 
Flammability
2
 
 
Reactivity
1
 

Health.
Exposure limit(s)
OEL-RUSSIA:STEL 5 mg/m3
Poison_Class
1
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
   Inhalation
Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Can produce delayed pulmonary edema. May cause burning sensation in the chest.
   Skin
Causes skin irritation. May cause irritation and dermatitis. May cause cyanosis of the extremities.
   Eyes
Causes eye irritation. Lachrymator. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2295
Response guide
Hazard class
6.1
Packing Group
I
 
USCG CHRIS Code
MED
 
HS Code
2915 40 00
 
Std. Transport #
4921781