Methyl chloromethyl ether

  • Chloromethoxymethane
  • Chloromethyl methyl ether
Formula
CH3OCH2Cl
Structure
Description
A clear colorless liquid.
Uses
Chemical int, eg, for dodecylbenzyl chloride.

Registry Numbers and Inventories.
CAS
107-30-2
EC (EINECS/ELINCS)
203-480-1
EC Index Number
603-075-00-3
EC Class
Highly flammable; Carcinogenic Category 1; Harmful
RTECS
KN6650000
RTECS class
Tumorigen; Mutagen
UN (DOT)
1239
Merck
12,2198
Beilstein/Gmelin
505943
Beilstein Reference
4-01-00-03046
RCRA
U046
Swiss Giftliste 1
G-4655
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H5ClO
Formula mass
80.51
Melting point, °C
-103.5
Boiling point, °C
59
Vapor pressure, mmHg
218 (25 C)
Vapor density (air=1)
2.8
Density
1.0972 g/cm3 (0 C)
Solubility in water
Reacts
Surface tension
approx 30 g/s2
Refractive index
1.39524 (20 C)
Partition coefficient, pKow
0.44
Heat of vaporization
28.9 kJ/mol
Heat of combustion
-1370 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid.
Stability
Vapor may explode if ignited in an enclosed area.
Incompatibilities
May react violently with strong oxidizing agents.
Decomposition
Decomposition in hot ethanol when heated to decomposition it emits toxic fumes of hydrogen chloride.

Fire.
Flash Point,°C
-6
Fire fighting
Move container from fire area. Dike fire control water for later disposal; do not scatter material. Cool containers that are exposed to flames with water. Withdraw immediately in case of rising sound from venting safety device or any discoloration of tank due to fire. Extinguish with dry chemicals, foam, or carbon dioxide. Water may be ineffective in extinguishing fire.
Fire potential
Very flammable.
Hazards
Flammable/combustible material; may be ignited by heat, sparks, or flames. Vapors may travel to a source of ignition and flash back. Container may explode in heat of fire. In addition to the risk of explosion, when air mixtures of ether vapors are heated or exposed to flame or sparks, they tend to form peroxides. Ethers containing peroxides can detonate when heated. Unburned material may form powerful tear gas. When wet, also forms irritating formaldehyde gas. Evolves formaldehyde and hydrogen chloride. When heated to decomposition, it emits toxic fumes of chlorides. Avoid decomposing heat
Combustion products
Reacts to evolve formaldehyde and hydrogen chloride: The reaction is not violent.
Health
3
 
Flammability
3
 
 
Reactivity
2
 

Health.
Exposure limit(s)
OSHA PEL: 1910.1006 See Appendix B NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen
Carcinogin
O, G-A2, I-1, N-1, CP65
Poison_Class
1*
Exposure effects
Dyspnea and fever may occur from vapor inhalation. No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation.
   Ingestion
Abdominal cramps, vomiting. See inhalation.
   Inhalation
Noncardiogenic pulmonary edema or chemical pneumonitis may be the cause of death in acute inhalation exposure.
   Skin
Burns and necrosis of the skin may occur from direct contact with the liquid.
   Eyes
Severe burns of the eyes may occur upon direct contact. Chloromethyl methyl ether is a lacrimator. The vapor is irritating to the nose and throat.

First aid
 
   Ingestion
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush with running water for at least 20 minutes. Wash skin with soap and water.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
1239
Response guide
Hazard class
6.1
PRTC
T
Packing Group
I
 
USCG CHRIS Code
CME
 
Std. Transport #
4927012