Methyl cyanoacrylate

  • Methyl 2-cyanoacrylate
  • 2-Propenoic acid, 2-cyano-, methyl ester
  • 2-Cyanoacrylic acid methyl ester
  • Eastman 910 Super Glue
  • Cyanobond 5000
  • Sicomet 7000
Formula
CH2=C(C N)COOCH3
Structure
Description
Clear slightly yellow liquid.
Uses
Mfg of polymers and adhesives, surgical aid (tissue adhesive).

Registry Numbers and Inventories.
CAS
137-05-3
EC (EINECS/ELINCS)
205-275-2
EC Index Number
607-235-00-3
EC Class
Irritant
RTECS
AS7000000
RTECS class
Mutagen; Reproductive Effector; Primary Irritant
Merck
12,5827
Beilstein/Gmelin
1751282
Beilstein Reference
4-02-00-02226
Swiss Giftliste 1
G-4649
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C5H5NO2
Formula mass
111.1
Boiling point, °C
48
Vapor pressure, mmHg
0.2
Vapor density (air=1)
3.8
Density
1.105 g/cm3 (20 C)
Solubility in water
Very soluble
Refractive index
1.4437 (20 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Suitable protective clothing & self-contained resp protective apparatus should be available for use of those who may have to rescue persons overcome by fumes. Acrylic acid & derivatives.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then use absorbent paper to pick up liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with toluene followed by washing with a soap and water solution. Do no reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
The substance polymerizes rapidly, especially under the influence of moisture.
Incompatibilities
Incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions Incompatible with other oxidizing agents such as peroxides and epoxides Can react vigorously with reducing agents Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.
Decomposition
Decomposes on heating or on burning producing toxic and irritating fumes/gases including nitrogen oxides. Reacts violently with water, bases and peroxides.

Fire.
Flash Point,°C
79
Fire fighting
Fires involving this compound should be controlled using a dry chemical, carbon dioxide, foam or Halon extinguisher.
Hazards
Flash point data for this compound are not available but it is probably non-flammable.

Health.
Exposure limit(s)
NIOSH REL: TWA 2 ppm (8 mg/m3) ST 4 ppm (16 mg/m3)
Poison_Class
1
Exposure effects
The toxological properties of this substance have not been fully investigated.
   Inhalation
Heating cyanoacrylate glues increases their volatility creating increased respiratory and eye irritation. Cyanide is not released.
   Skin
Minimal skin irritation may be noted. Most irritation occurs where bonded surfaces are pulled apart mechanically.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.