Methyl ethyl ketone

  • Ethyl methyl ketone
  • Butanone
  • MEK
  • Methyl acetone
Formula
CH3COC2H5
Structure
Description
Clear, colorless liquid with a sharp mint-like odor.
Uses
As solvent, in the surface coating industry, manufacture of colorless synthetic resins, smokeless powder.

Registry Numbers and Inventories.
CAS
78-93-3
EC (EINECS/ELINCS)
201-159-0
EC Index Number
606-002-00-3
EC Class
Highly flammable; Irritant; Repeated exposure may cause skin dryness or cracking; Vapours may cause drowsiness and dizziness
R 11 36 66 67
RTECS
EL6475000
RTECS class
Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
1193
Merck
12,6149
Beilstein/Gmelin
741880
Beilstein Reference
4-01-00-03243
RCRA
U159
EPA OPP
44103
Swiss Giftliste 1
G-2429
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H8O
Formula mass
72.11
Melting point, °C
-86
Boiling point, °C
79.6
Vapor pressure, mmHg
89 (25 C)
Vapor density (air=1)
2.5
Saturation Concentration
10.2% at 20 C
Evaporization number
2.7 (diethyl ether=1)
Odor Threshold Odor threshold 0.7375 mg/m3
Critical temperature
262.5
Critical pressure
43.3
Density
0.8054 g/cm3 (20 C)
Solubility in water
290 g/L (20 C)
Viscosity
0.41 cp @ 20C
Surface tension
24.6 g/s2 @ 20 C
Refractive index
1.3814 (20 C)
Dipole moment
2.7 D (20 C)
Dielectric constant
18.85 (20 C)
Partition coefficient, pKow
0.29
Heat of fusion
6.78 kJ/mol
Heat of vaporization
35.6 kJ/mol
Heat of combustion
-2438 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B2 D2A D2B
Handling
Use only in a well ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing materials, caustics, amines, ammonia, strong bases, chloroform, chlorosulfonic acid, oleum, potassium-t-butoxide, heat or flame, hydrogen peroxide, nitric acid. Can attack many plastics, resins and rubber.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
-9
Autoignition, °C
516
Upper exp. limit, %
11.4
Lower exp. limit, %
1.4
Fire fighting
Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Extinguish with dry chemical, foam or carbon dioxide. Water spray may be used to keep fire exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA PEL: TWA 200 ppm (590 mg/m3) NIOSH REL: TWA 200 ppm (590 mg/m3) ST 300 ppm (885 mg/m3) NIOSH IDLH: 3000 ppm
Poison_Class
5
Exposure effects
Chronic inhalation may cause effects similar to those of acute inhalation. Prolonged or repeated skin contact may cause defatting and dermatitis. Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen.
   Ingestion
May produce abdominal pain, nausea. Aspiration into lungs can produce severe lung damage and is a medical emergency. Other symptoms expected to parallel inhalation.
   Inhalation
Causes irritation to the nose and throat. Concentrations above the TLV may cause headache, dizziness, nausea, shortness of breath, and vomiting. Higher concentrations may cause central nervous system depression and unconsciousness.
   Skin
Causes irritation to skin. Symptoms include redness, itching, and pain. May be absorbed through the skin with possible systemic effects.
   Eyes
Vapors are irritating to the eyes. Splashes can produce painful irritation and eye damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Rinse area with large amounts of water for at least 15 minutes. Remove contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
1193
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
MEK
 
HS Code
2914 12 00
 
Std. Transport #
4907802
 
IMO Chemical Code
18
IMO Pollution Category
III