Methyl magnesium chloride

  • Chloromethylmagnesium
Formula
CH3ClMg
Structure
Description
Dark liquid.
Uses
Alkylating agent in organic synthesis, grignard reagent.

Registry Numbers and Inventories.
CAS
676-58-4
EC (EINECS/ELINCS)
211-629-7
UN (DOT)
2813
Beilstein/Gmelin
3587199
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
CH3ClMg
Formula mass
74.79
Boiling point, °C
66
Density
1.03 g/cm3

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Keep away from water. Water free area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources and prevent contact. Stop leak if you can do it without risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. However DO NOT GET WATER on spilled substance or inside containers. Cover with DRY earth, DRY sand, or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. For powers, cover with plastic sheet or tarp to minimize spreading and keep powder dry. DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST.
Stability
No data.
Incompatibilities
Oxidizing agents, acids, alcohols.
Decomposition
Hydrogen chloride, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
-17
Autoignition, °C
212
Upper exp. limit, %
12.0
Lower exp. limit, %
1.5
Fire fighting
DO NOT USE WATER OR FOAM. Small Fire: Dry chemical, soda ash, lime or sand. Large Fires: DRY sand, dry chemical, soda ash or lime or withdraw from area and let fire burn.
Fire potential
Dangerous fire risk.
Hazards
May ignite on contact with water or moist air. Some react vigorously or explosively on contact with water. May be ignited by heat, sparks or flames. May re-ignite after fire is extinguished. May be transported in highly flammable liquids.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Lethargy, hyporeflexia, weakness, and subjective feeling of thirst and heat may occur. Excessive absorption of magnesium from cathartics may result in CNS depression and seizures, most notably in renal failure patients.
   Inhalation
Inhalation or contact with vapors, substance, or decomposition products may cause severe injury or death.
   Skin
Cutaneous flushing may be noted.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Activated charcoal does not effectively adsorb magnesium salts. Monitor ecg and vital signs frequently. Cardiovascular and/or respiratory assistance may be required. Calcium - to temporarily ameliorate respiratory depression, administer iv calcium chloride 10% (dose: 0.2 To 0.5 Ml/kg/dose up to 10 ml/dose over 5 to 10 minutes). Monitor ecg during infusion and stop if heart rate begins to decrease. Repeat dose if needed. Hypotension: infuse 10 to 20 ml/kg isotonic fluid, place in trendelenburg position. If hypotension persists, administer dopamine (5 to 20 mcg/kg/min) or norepinephrine (0.1 To 0.2 Mcg/kg/min), titrate to desired response. Hypothermia - place patient under a warming blanket or a hugg-bear or equivalent device. Hemodialysis - is the most effective method to remove significant quantities of magnesium and may reverse life-threatening symptoms within 30 minutes.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing, wash exposed area with copious amounts of water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Medical facility: irrigate with sterile 0.9% Saline for at least an hour.

Transport.
UN number
2813
Response guide
Hazard class
4.3
Packing Group
I; II; III