Methyl methanesulfonate

  • as-Dimethyl sulfite
  • as-Dimethyl sulphite
  • Methyl mesylate
  • Methylmethane sulfonate
  • Methyl methanesulfonic acid
  • Methylmethanesulphonate
Formula
C2H6O3S
Structure
Description
Colorless to amber liquid.
Uses
Research chemical.

Registry Numbers and Inventories.
CAS
66-27-3
EC (EINECS/ELINCS)
200-625-0
RTECS
PB2625000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector
UN (DOT)
2922
Merck
12,6170
Beilstein/Gmelin
1098586
Beilstein Reference
4-04-00-00011
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C2H6O3S
Formula mass
110.12
Melting point, °C
20
Boiling point, °C
203
Vapor pressure, mmHg
0.42 (25 C)
Density
1.3206 g/cm3 (0 C)
Solubility in water
Very soluble
Refractive index
1.41248 (16.2 C)
Partition coefficient, pKow
-0.57
Heat of vaporization
42.0 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents - strong acids - strong bases.
Decomposition
Carbon monoxide, oxides of sulfur, carbon dioxide.

Fire.
Flash Point,°C
104
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This chemical is combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Carcinogin
I-2A, N-2, CP65
Exposure effects
   Ingestion
See inhalation.
   Inhalation
Symptoms of exposure to this compound may include irritation of the eyes, skin, mucous membranes, nose and respiratory tract. It can cause dermatitis and nausea. Large doses ingested over nearly a year produced gastrointestinal and hepatic toxic effects.
   Skin
See inhalation.
   Eyes
See inhalation

First aid
 
   Ingestion
Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2922
Response guide
Hazard class
8
Packing Group
I; II; III