Methyl vinyl ketone

  • 3-Buten-2-one
  • Methylene acetone
  • Acetyl ethylene
  • Butenone
Formula
CH3COCH=CH2
Structure
Description
Colorless to light yellow liquid with strong odor, lachrymator.
Uses
Alkylating agent, commercial starting material for plastics, as intermediate in synthesis of steroids & vitamin a.

Registry Numbers and Inventories.
CAS
78-94-4
EC (EINECS/ELINCS)
201-160-6
EC Class
highly flammable, very toxic, corrosive, carcinogenic,&
R 11 26/28 34
S 16 26 28 36/37/39 45
RTECS
EM9800000
RTECS class
Mutagen
UN (DOT)
1251
Merck
12,6214
Beilstein/Gmelin
506021
Beilstein Reference
4-01-00-0344
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H6O
Formula mass
70.09
Melting point, °C
-7
Boiling point, °C
81.4
Vapor pressure, mmHg
84 (25 C)
Vapor density (air=1)
2.41
Saturation Concentration
160,000 ppm at 34 C (calc.)
Odor Threshold Odor threshold 0.5 mg/m3
Density
0.8636 g/cm3 (20 C))g/cm3 (20 C)
Solubility in water
Soluble
Viscosity
0.807 cp at 70 deg f
Surface tension
24 g/s2
Refractive index
1.4086 (20 C)
Partition coefficient, pKow
0.117
Heat of vaporization
32.2 kJ/mol
Heat of combustion
-2317 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated location. Store away from heat, oxidizing materials, and sunlight. Separate from alkalies, reducing agents. Outside or detached storage is preferred.
B2 D1A E
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid. Apply water spray or mist to knock down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Water spill: Use natural barriers or oil spill control booms to limit spill travel. Remove trapped material with suction hoses.
Disposal code
9
Stability
Polymerizes on standing.
Incompatibilities
Incompatible with strong oxidizers and strong bases.

Fire.
Flash Point,°C
-8
Autoignition, °C
491
Upper exp. limit, %
15.6
Lower exp. limit, %
2.1
Fire fighting
Use water to keep fire-exposed containers cool. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Wear positive pressure breathing apparatus and special protective clothing. Isolate for 1/2 mile in all directions if tank car or truck is involved in fire.Use dry chemical, alcohol foam, or carbon dioxide. Water spray may be ineffective as an extinguishing agent. Small fires: dry chemical, carbon dioxide, and foam. Large fires: fog or foam. Move container from fire area if you can do so without risk. Dike fire control water for later disposal; do not scatter the material. Spray cooling water on containers that are exposed to flames until well after fire is out. Withdraw immediately in case of rising sound from venting safety device or any discoloration of tank due to fire.
Fire potential
Dangerous, when exposed to heat, flame or oxidizers. Flammable liquid.
Hazards
Vapors form flammable mixtures with air, and may travel a considerable distance to a source of ignition and flash back. Polymerization may take place in containers, possibly with violent rupture of containers. Upon exposure to heat or flame, it emits toxic and irritating fumes. Container may explode in heat of fire. Vapor explosion and poison hazard indoors, outdoors, or in sewers. Polymerizes on standing. Hazardous polymerization may occur. Avoid heat or sunlight.
Combustion products
Dangerous, upon exposure to heat or flame; emits toxic and irritating fumes..
Health
4
 
Flammability
3
 
 
Reactivity
2
 

Health.
Exposure effects
Reduced body temperature may be noted. Inhalation of high concentrations of ketones produce CNS depressant effects, including headache, dizziness, fainting, tremor, incoordination, lowered body temperature, depressed respirations and heart rate, dyspnea, gasping, coma, and death. Skin exposure to vapor or liquid may result in paresthesia of affected areas. No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation. <br>No information about possible male reproductive effects was found in available references.
   Ingestion
See inhalation.
   Inhalation
May be fatal. May cause irritatior or burns. Vapors may cause dizziness or suffocation.
   Skin
Skin exposure to vapor or liquid may result in dermatoses and paresthesia of affected area. Methyl vinyl ketone can be readily absorbed through the skin, and is severely irritating to the skin (sometimes causing blistering).
   Eyes
See inhalation.

First aid
 
   Ingestion
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush with running water for at least 20 minutes. Wash skin with soap and water.
   Eyes
In case of contact with substance, immediately flush with running water for at least 20 minutes.

Transport.
UN number
1251
Response guide
Hazard class
6.1
PRTC
T
Packing Group
I
 
USCG CHRIS Code
MVK
 
HS Code
2914 19 90
 
Std. Transport #
4927022