Methylene blue trihydrate

  • C.I. basic blue 9, trihydrate
  • 3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate
  • Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride, trihydrate
Formula
C16H18ClN3S.xH2O
Structure
Description
Odorless or almost odorless dark green crystals with bronze luster or dark green crystalline powder. Hygroscopic.
Uses
Stain, indicator, disinfectant.

Registry Numbers and Inventories.
CAS
7220-79-3
RTECS
SP5740000
RTECS class
Tumorigen
Beilstein/Gmelin
NA
New Zealand
Listed

Properties.
Formula
C16H18ClN3S.xH2O
Formula mass
373.94
Decomposition point, °C
190
Vapor density (air=1)
13

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal shipping and handling conditions. However, may decompose if heated.
Incompatibilities
Strong oxidizing agents, strong reducing agents, alkalis, dichromates, alkali iodides.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
This material is probably combustible.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed.
   Inhalation
Dust is irritating to the respiratory tract. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death.
   Skin
May cause skin irritation.
   Eyes
Causes eye burns. This product contains a cationic dye. Similar dyes have caused permanant injury to the cornea and conjunctiva in documented exposure cases with human or rabbit eyes.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Transport.
Hazard class
6.1