Methylglutaronitrile

  • 2-Methylpentanedinitrile
  • 1,3-Dicyanobutane
  • Diacrylonitrile
Formula
C6H8N2
Structure
Description
Amber liquid.
Uses
Used as a solvent and intermediate for the manufacture of other chemicals.

Registry Numbers and Inventories.
CAS
4553-62-2
EC (EINECS/ELINCS)
224-923-5
EC Class
harmful
R 21/22
RTECS
YV8140000
RTECS class
Mutagen
UN (DOT)
3276
Beilstein/Gmelin
1741955
Beilstein Reference
4-02-00-01990
Swiss Giftliste 1
G-5371
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C6H8N2
Formula mass
108.16
Melting point, °C
-45
Boiling point, °C
260
Vapor pressure, mmHg
0.01 (25 C)
Density
0.9548 g/cm3 (20 C)
Solubility in water
Very soluble
Refractive index
1.4355 (20 C)
Partition coefficient, pKow
-0.37
Heat of vaporization
49.8 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Small spills/leaks
Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions Incompatible with other oxidizing agents such as peroxides and epoxides Can react vigorously with reducing agents.

Fire.
Flash Point,°C
109
Upper exp. limit, %
3.25
Lower exp. limit, %
0.3
Fire fighting
Fires involving this compound can be controlled by dry chemical, carbon dioxide, and/or Halon extinguishers.
Fire potential
This compound is combustible.

Health.
Poison_Class
2
Exposure effects
   Ingestion
Anorexia may be noted in patients exposed chronically, while nausea and vomiting are seen in acute exposures. Vomiting has preceded serious toxicity within several hours in most cases of ingestion.
   Inhalation
Hyperpnea, respiratory insufficiency, kussmaul respirations, and chest tightness have been reported.
   Skin
Splash contact with the liquid may cause faint erythema of short duration. Chronic exposure may produce maculopapular vesicular dermatitis.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
3276
Response guide
HS Code
2926 90 95