Methylmaleic anhydride

  • Citraconic acid anhydride
  • Citraconic anhydride
  • alpha-Methylmaleic anhydride
  • 2-Methylmaleic anhydride
  • 3-Methylmaleic anhydride
  • Monomethylmaleic anhydride
Formula
C5H4O3
Structure
Description
Colorless liquid.
Uses
Reagent for alkalies, alcohols, and amines.

Registry Numbers and Inventories.
CAS
616-02-4
EC (EINECS/ELINCS)
210-459-0
EC Class
toxic, irritant, sensitizing
R 24 36/38
S 26 28 36/37/39 45
RTECS
GE6825000
RTECS class
Primary Irritant
UN (DOT)
2810
Beilstein/Gmelin
1835
Beilstein Reference
5-17-11-00065
Swiss Giftliste 1
G-2512
Canada DSL/NDSL
DSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C5H4O3
Formula mass
112.08
Melting point, °C
8 - 12
Boiling point, °C
213
Vapor pressure, mmHg
10 (47 C)
Vapor density (air=1)
1.247
Density
1.2649 g/cm3 (0 C)
Solubility in water
Insoluble
Refractive index
1.47 (15.4 C)
Partition coefficient, pKow
0.23
Heat of vaporization
44.8 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents, moisture.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
101
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Epichlorohydrin ingestion has resulted in cyanosis, muscular relaxation or paralysis, tremor, seizures, and respiratory arrest in animal studies.
   Ingestion
May cause irritation of the digestive tract. May cause cardiac disturbances. May cause central nervous system depression.
   Inhalation
May cause respiratory tract irritation. May cause cardiac abnormalities. Inhalation at high concentrations may cause CNS depression and asphixiation.
   Skin
May cause skin irritation. Harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
11 Organic anhydrides
HS Code
2917 19 90