Methylpyridine

  • Picoline
Formula
C6H7N
Structure
Description
Clear colorless liquids with a strong unpleasant odor.
Uses
Intermediate in dye and resins industry, solvent 2- and 3-methylpyridine.

Registry Numbers and Inventories.
CAS
1333-41-1
EC (EINECS/ELINCS)
215-588-6
UN (DOT)
2313
Beilstein/Gmelin
4798959
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H7N
Formula mass
93.13
Melting point, °C
2.4
Boiling point, °C
145
Vapor pressure, mmHg
11.2 (25 C)
Density
0.957 g/cm3 (20 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Depending on the extent of possible contact, workers should be provided with personal protective equipment. Rubber and plastic gloves should not be relied upon to prevent skin contact because pyridine and many of its derivatives penetrate these materials.
Respirators
A charcoal gas mask canister respirator has been found to be effective against a 2% pyridine concentration at 30 L/min for 1 hr.
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid.
Stability
No data.
Incompatibilities
Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Fire.
Autoignition, °C
537
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use alcohol foam, dry chemical or carbon dioxide.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Emits toxic fumes under fire conditions.
Health
3
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure effects
No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation. <br>Animal studies on chick for substituted pyridines have shown teratogenicity. Injected chicken eggs develop leg and skeletal malformations.
   Ingestion
Irritation may result in abdominal pain with vomiting, or diarrhea.
   Inhalation
Severe acute intoxications may result in respiratory depression and death.
   Skin
Skin irritation may result from repeated or prolonged exposure or photosensitivity.
   Eyes
See Skin.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
CALL FOR MEDICAL AID. Remove victim to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating eyelids with fingers.

Transport.
UN number
2313
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
MPF
 
9 Aromatic amines
Std. Transport #
4909179
 
IMO Pollution Category
D
IMO Hazard code
S