Metribuzin

  • 4-Amino-6-tert-butyl-3-methylthio-as-triazin-5-one
  • 4-Amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one
Formula
C8H14N4OS
Structure
Description
Colorless crystalline solid.
Uses
Herbicide

Registry Numbers and Inventories.
CAS
21087-64-9
EC (EINECS/ELINCS)
244-209-7
EC Index Number
606-034-00-8
EC Class
Harmful; Dangerous for the Environment
RTECS
XZ2990000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector
Merck
12,6239
Beilstein/Gmelin
746650
Beilstein Reference
5-26-06-00432
EPA OPP
101101
Swiss Giftliste 1
G-6406
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C8H14N4OS
Formula mass
214.29
Melting point, °C
126
Boiling point, °C
132 (0.1 torr)
Vapor pressure, mmHg
4E-7
Density
1.24 g/cm3
Solubility in water
1.2 g/L
pKa/pKb
1.0 (pKa)
Partition coefficient, pKow
1.7

Hazards and Protection.
Storage
Estimated shelf life in excess of 2 yr under normal storage conditions store in a cool, dry place. Do not contaminate water or feed by storage or disposal.
Handling
Untrained persons should not handle this chemical or its containers. Avoid contact with eyes, skin and clothing. Avoid breathing vapors.. For laboratory use only.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use appropriate OSHA/MSHA approved respirator.
Small spills/leaks
Evacuate area. Wear OSHA regulated equipment. Ventilate area. Sweep up and place in a n approved container. Hold for disposal. Wash contaminated surfaces to remove any residue.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
When heated to decomposition it emits very toxic fumes of nitrogen oxides and sulfur oxides.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Fire potential
Nonflammable

Health.
Exposure limit(s)
TLV: ppm; 5 mg/m3 (as TWA) (ACGIH 1997). OSHA PEL: none NIOSH REL: TWA 5 mg/m3
Poison_Class
4
Exposure effects
Coma was reported following ingestion of an herbicide containing atrazine, aminotriazole, ethylene glycol, and formaldehyde. Muscle tremors, tetany, and ataxia have been reported in animals following ingestions of triazine herbicides.
   Ingestion
See inhalation.
   Inhalation
Symptoms: In animals: central nervous system depressant/depression; thyroid, liver enzyme changes Target Organs: central nervous system, thyroid, liver.
   Skin
See inhalation.
   Eyes
See inhalation.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.