Miltefosine

  • Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt
  • 2-Hexadecylphosphorylcholine
Formula
C21H46NO4P
Structure
Description
Crystalline solid.

Registry Numbers and Inventories.
CAS
58066-85-6
RTECS
KH2890000
Merck
12,6285
Beilstein/Gmelin
3690495
Beilstein Reference
4-04-00-01460

Properties.
Formula
C21H46NO4P
Formula mass
407.57
Melting point, °C
224 - 226
Solubility in water
2.5 g/L (25 C)

Hazards and Protection.
Protection
Protection Safety glasses. Latex disposable gloves. Lab coat.
Small spills/leaks
Vacuum or sweep up material and place in disposal container. After removal, ventilate contaminated area and flush thoroughly with water.
Stability
Stable at normal temperatures and pressures.

Fire.
Fire fighting
Use alcohol foam, carbon dioxide, or water spray when fighting fires involving this material. Wear self-contained breathing apparatus pressure-demand (MSHA/NIOSH approved or equivalent), and full protective gear to prevent contact with skin and eyes.

Health.
Exposure effects
Irritating to the skin, eyes, nose, throat, and respiratory tract.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Never give anything by mouth to an unconscious person. Get medical attention.
   Inhalation
If inhaled remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained personnel. Get immediate medical attention.
   Skin
In case of skin contact, immediately wash skin with soap and plenty of water. Remove contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse. Note to Physician.
   Eyes
In case of contact with eyes, hold eyelids apart and flush eyes with plenty of water. After initial flushings, remove any contact lenses and continue flushing for at least 15 minutes. Have eyes examined and tested by medical personnel.

Transport.