Mizoribine

  • Anhydro-4-carbamoyl-5-hydroxy-1-b-D-ribofuranosyl-imidazolium-hydroxide
  • Bredinin
  • 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide
  • 4-Carbamoyl-1-beta-D-ribofuranosyl-imidazolium-5-olate
  • HE-69
  • 1H-Imidazole-4-carboxamide, 5-hydroxy-1-beta-D-ribofuranosyl
Formula
C9H13N3O6
Structure

Registry Numbers and Inventories.
CAS
50924-49-7
RTECS
NI3980000
Merck
12,6306
Beilstein/Gmelin
4151713

Properties.
Formula
C9H13N3O6
Formula mass
259.22
Density
2.06 g/cm3 (20 C)
Solubility in water
1.4 g/L (25 C)
pKa/pKb
6.89 (pKa)
Partition coefficient, pKow
-0.17

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Oxides of carbon, oxides of nitrogen.

Fire.
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May be harmful by inhalation, ingestion, or skin absorption. Reported to have immunosuppressive effect, causing decrease in number of leucocytes.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.