Molinate

  • s-Ethyl-n-hexahydro-1h-azepinthiolcarbamat
  • S-Ethyl azepane-1-carbothioate
  • S-Ethyl hexahydro-1H-Azepine-1-carbothioate
  • Ethyl 1-Hexamethyleneiminecarbothiolate
  • Jalan
Formula
C9H17NOS
Structure
Description
Clear liquid with aromatic odor.
Uses
Herbicide

Registry Numbers and Inventories.
CAS
2212-67-1
EC (EINECS/ELINCS)
218-661-0
EC Index Number
613-051-00-4
EC Class
Harmful
RTECS
CM2625000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector
Beilstein/Gmelin
1239196
Beilstein Reference
5-20-04-00034
RCRA
U365
EPA OPP
41402
Swiss Giftliste 1
G-6592
Austrailia AICS
Listed
Korea ECL
Listed

Properties.
Formula
C9H17NOS
Formula mass
187.33
Boiling point, °C
202
Vapor pressure, mmHg
0.0057 (25 C)
Density
1.063 g/cm3 (20 C)
Solubility in water
970 mg/L (25 C)
Refractive index
1.5092 (25 C)
Partition coefficient, pKow
3.21

Hazards and Protection.
Storage
Store away from food and feedstuffs and out of reach of children.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear protective clothing; wash it thoroughly after use.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Stable at 100 C for 16 hours apparently indefinite storage life under ambient conditions; photosensitivity is indeterminant relatively stable to hydrolysis by acids and alkalies. Stable @ < 200 C.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Fire potential
Fire point= 143 C.

Health.
Poison_Class
4
Exposure effects
Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.
   Ingestion
Nausea, vomiting and diarrhea may occur.
   Inhalation
Respiratory failure, requiring ventilatory support, has been reported following ingestions.
   Skin
Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.

First aid
 
   Ingestion
Ipecac induced vomiting is not recommended because of the potential for cns depression and seizures. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Intravenous fluids may be useful in restoring extracellular fluid volume following severe vomiting and diarrhea. Oxygen therapy is effective in relieving the distress of antabuse-like reactions rarely associated with exposure to thiram and possibly the mbdt-carb compounds. No specific antidotes are available for poisoning by these compounds. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.