Monensin sodium

  • Coban
  • Coban-45
  • Monensin, monosodium salt
  • Rumensin
  • Monensin-sodium salt
  • 1,6-Dioxaspiro(4.5)decane-7-butyric acid, 2-(5-ethyltetrahydro-5-(tetrahydro-3-methyl-5- (tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl)-2-furyl)-2-furyl)-9- hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-, monosodium salt
Formula
C36H61NaO11
Structure
Description
Almost white solid.
Uses
A polyether ionophore produced by Streptomyces cinnamonensis that exhibits both antibacterial and anticoccidial activities.

Registry Numbers and Inventories.
CAS
22373-78-0
EC (EINECS/ELINCS)
244-941-7
RTECS
JH2830000
RTECS class
Other
UN (DOT)
2811
Beilstein/Gmelin
4122200
Canada DSL/NDSL
DSL
New Zealand
Listed

Properties.
Formula
C36H61O11*Na
Formula mass
692.86
Melting point, °C
269

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Moisture, heat.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May be fatal if swallowed. May cause irritation of the digestive tract. May cause fever, muscle and joint pain, and convulsions. Ingestion may cause weakness, ataxia, diarrhea, and unconsciousness.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III