N-Isopropylaniline

  • N-(1-Methylethyl)benzenamine
  • N-Phenylisopropylamine
Formula
C9H13N
Structure
Description
Clear brown liquid.
Uses
Dyeing acrylic fibers, chemical intermediate.

Registry Numbers and Inventories.
CAS
768-52-5
EC (EINECS/ELINCS)
212-196-7
R 22 23
S 28 36/37 45
RTECS
BY4190000
RTECS class
Primary Irritant
UN (DOT)
2810
Beilstein/Gmelin
2205871
Beilstein Reference
4-12-00-00255
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C9H13N
Formula mass
135.23
Melting point, °C
-50
Boiling point, °C
202
Vapor pressure, mmHg
0.03
Density
0.93 g/cm3 (20 C)
Refractive index
1.5394 (20 C)
pKa/pKb
8.70 (pKb)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate eye protection and protective clothing to prevent skin and eye contact. Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Decomposition
When heated to decomposition it emits toxic fumes of oxides of nitrogen.

Fire.
Flash Point,°C
87.8
Fire fighting
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or halon extinguisher.
Fire potential
This chemical is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
TLV: 2 ppm; 11 mg/m3 (skin) (ACGIH 1992-1993). NIOSH REL: TWA 2 ppm (10 mg/m3) skin
Exposure effects
Acute poisoning may cause rapid heart rate and rapid breathing. Severe headache, CNS disturbances, and tremor may occur. A high incidence of gynecological disorders and excess frequency of spontaneous abortions have been noted. The fetal liver can n-oxygenate aniline to form phenylhydroxylamine. Fetal effects include higher levels of methemoglobin those found in than the mother. Fetal poisoning may occur. <br>No data were available to assess the potential effects of exposure to aniline during lactation. <br>No information about possible male reproductive effects was found in available references at the time of this review
   Ingestion
Nausea and vomiting can occur.
   Inhalation
Signs of hypoxia may be present.
   Skin
Dermal absorption is rapid. Cyanosis, moderate skin irritation and sensitization, and dermatitis have been noted.
   Eyes
Cyanosis may occur. Corneal damage, discoloration, and mild to severe irritation of the eyes have been noted.

First aid
 
   Ingestion
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
9. Aromatic amines