N-Methylolacrylamide

  • n-(Hydroxymethyl)-2-propenamide
  • n-Methanolacrylamide
  • n-Methylolacrylamide
  • Monomethylolacrylamide
  • Uramine tT 80
  • Rocagil BT
Formula
C4H7NO2
Structure
Description
A colorless or yellow aqueous solution.
Uses
Proposed for use in sunscreen preparations. Reactive comonomer, starch modifier.

Registry Numbers and Inventories.
CAS
924-42-5
EC (EINECS/ELINCS)
213-103-2
RTECS
AS3600000
RTECS class
Tumorigen; Mutagen; Reproductive Effector
Beilstein/Gmelin
506646
Beilstein Reference
4-02-00-01472
Swiss Giftliste 1
G-6424
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H7NO2
Formula mass
101.10
Melting point, °C
79 - 81
Boiling point, °C
290
Critical temperature
518
Critical pressure
53.5
Density
1.1 g/cm3
Solubility in water
Very soluble
pKa/pKb
13.25 (pKa)
Partition coefficient, pKow
-0.28

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
May be sensitive to prolonged exposure to light Incompatible with strong oxidizers.
Decomposition
When heated to decomposition it emits toxic fumes of nitrogen oxides.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is nonflammable

Health.
Carcinogin
CP65
Poison_Class
2
Exposure effects
Abnormally low blood pressure, rapid heart rate, respiratory depression, reduced body temperature, and cardiovascular collapse may occur.
   Ingestion
Anorexia and gastrointestinal disturbances may be seen in patients with sub-acute exposure. Pancreatitis following ingestion has been reported.
   Inhalation
A persistent cough has been reported in sub-acute ingestions, but pulmonary findings were absent.
   Skin
An exfoliative, erythematous rash of the hands may be seen with chronic dermal exposure.
   Eyes
Visual impairment and eye irritation may occur. Rhinorrhea and mucosal irritation may occur in sub-acute exposures.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.