N-Nitroso-n-Methylurethane

  • Ethyl n-methylnitrosocarbamate
  • n-Methyl-n-nitrosoethylcarbamate
  • n-Methyl-n-Nitrosourethan
  • Methylnitrosourethane
  • n-Methyl-n-Nitrosourethane
  • Mnun
Formula
C4H8N2O3
Structure
Description
Yellow to pink oil. Sweet smelling.
Uses
Research chemical, laboratory preparation of diazomethane (former use).

Registry Numbers and Inventories.
CAS
615-53-2
EC (EINECS/ELINCS)
210-432-3
RTECS
FC6300000
RTECS class
Tumorigen; Mutagen; Reproductive Effector
Beilstein/Gmelin
1763954
Beilstein Reference
4-04-00-03385
RCRA
U178
Swiss Giftliste 1
G-5325
Canada DSL/NDSL
NDSL
US TSCA
Listed
Korea ECL
Listed

Properties.
Formula
C4H8N2O3
Formula mass
132.11
Melting point, °C
<-20
Boiling point, °C
70 (27 torr)
Vapor pressure, mmHg
1
Density
1.133 g/cm3 (15 C)
Solubility in water
37,000 mg/L @ 25 C
Refractive index
1.4357 (19 C)

Hazards and Protection.
Storage
Store at stocks in the dark at less than -10 C in tightly closed containers. Protect from moisture. Store at working quantities and its solutions in a safety refrigerator in the laboratory work area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Dispensers of liquid detergent should be available. Protective suits (preferably disposable, one-piece and close-fitting at ankles and wrists), gloves, hair covering and overshoes. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators when working with particulates or gases. Protective clothing should be a distinctive color.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Diazomethane, a highly explosive gas is produced upon alkaline hydrolysis. Decomposition products may be explosive. Sealed bottles may explode at room temperature due to gas pressure. The compound is unstable and will explode when distilled at atmospheric pressure. It may become explosive if stored above 15 C.
Incompatibilities
Incompatible with strong acids and bases Incompatible with strong reducing agents such as hydrides Incompatible with oxidizing acids, peroxides, and hydroperoxides.

Fire.
Fire fighting
Foam, dry chemical, or carbon dioxide. (Safds* 0001).
Fire potential
Alkaline hydrolysis gives the highly flammable and explosive gas diazomethane.

Health.
Carcinogin
I-2B, CP65
Poison_Class
1*
Exposure effects
   Ingestion
Nausea, vomiting and diarrhea are possible if ingested.
   Inhalation
Cough, tachypnea, and wheezing are common after inhalation.
   Skin
Redness, swelling and pain may occur.

First aid
 
   Ingestion
Emesis is not indicated due to the irritant nature of these agents. Charcoal - not recommended; it may promote vomiting and make endoscopic evaluation difficult. Dilution: immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 4 ounces/120 ml in a child). Neutralization - neutralization is not indicated. Although these agents are irritants, and therefore should not produce tissue damage, it is almost impossible to assure that a particular substance under a particular set of circumstances would not cause damage. Therefore, each patient should be examined with the idea that mucous membrane damage might have occurred.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. If in a medical facility, sterile saline should be used to irrigate the eyes until the cul de sac is returned to neutrality. Some alkali exposures may require prolonged irrigation.

Transport.
USCG CHRIS Code
NMU