N-Nitrosomethylvinylamine

  • N-Methyl-N-nitroso-ethenylamine
  • N-Methyl-N-nitrosovinylamine
  • Methylvinylnitrosamine
  • Mvna
  • NMVA
Formula
C3H6N2O
Structure
Description
Very volatile yellow liquid.
Uses
N-nitroso compounds are produced primarily as research chemicals and not for commercial purposes. N-nitroso compounds.

Registry Numbers and Inventories.
CAS
4549-40-0
RTECS
YZ0875000
RTECS class
Tumorigen; Mutagen
Beilstein/Gmelin
2070750
RCRA
P084
Swiss Giftliste 1
G-5264

Properties.
Formula
C3H6N2O
Formula mass
86.11
Boiling point, °C
47
Solubility in water
soluble

Hazards and Protection.
Storage
Storage should be close to laboratory where material is to be used, so that only small amounts need to be carried. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
Unstable; concn decr of more than 10% has been observed in aqueous solution over 24 hr; light sensitive, esp to UV light.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Health.
Carcinogin
I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
Seizures, cerebral edema, headache, and malaise have been reported. Fetal death, fetotoxicity, and other teratogenic effects were observed in rat and mouse studies. Pre- and post-implantation mortality and abortion were observed in rats. Abnormal changes in sperm morphology were detected in mice.
   Ingestion
Vomiting, gastrointestinal hemorrhage, and peritonitis have occurred.
   Inhalation
Pulmonary edema, congestion, and hemorrhagic areas have been reported.

First aid
 
   Ingestion
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
USCG CHRIS Code
NMV