N-Phenyl-p-phenylenediamine

  • 4-Aminodiphenylamine
  • N-(4-aminophenyl)aniline
Formula
C12H12N2
Structure
Description
Odorless purple-black solid or flake or dark purple chips.
Uses
Constituent of hair dyes.

Registry Numbers and Inventories.
CAS
101-54-2
EC (EINECS/ELINCS)
202-951-9
EC Class
harmful, irritant, sensitizing
R 20/22 36/38
S 22 26 36/37/39
RTECS
ST3150000
RTECS class
Tumorigen; Mutagen; Primary Irritant
UN (DOT)
1673
Beilstein/Gmelin
908935
Beilstein Reference
4-13-00-00113
Swiss Giftliste 1
G-8591
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C12H12N2
Formula mass
184.24
Melting point, °C
72 - 75
Boiling point, °C
354
Vapor pressure, mmHg
3E-5 (25 C)
Vapor density (air=1)
6.4
Critical temperature
594
Critical pressure
31.5
Density
1.15 g/cm3 (20 C)
Solubility in water
Slightly soluble
Viscosity
1.76x10-2 pa.s @ 25C
Surface tension
3.08x10-2 n/m @ 25 C
pKa/pKb
8.80 (pKb)
Partition coefficient, pKow
1.29
Heat of vaporization
92.6 kJ/mol
Heat of combustion
-6290 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents - strong acids.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
198
Autoignition, °C
>500
Upper exp. limit, %
5.5
Lower exp. limit, %
0.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.
Fire potential
This chemical is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Abnormally low blood pressure and labored respirations may occur. CNS depression and peripheral neuropathy have been reported after ingestion.
   Ingestion
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1673
Response guide
Hazard class
6.1
Packing Group
III
 
9. Aromatic amines
HS Code
2921 59 90