N,N-Diethyl-m-toluamide

  • Benzamide
  • N,N-Diethyl-3-methyl-N,N-diethyl-3-methylbenzamide
  • Diethyltoluamide
  • Diethyl-m-toluamide
  • 3-Methyl-N,N-diethylbenzamide
Formula
CH3C6H4CN(C2H5)2O
Structure
Description
Water white to amber liquid, nearly odorless.
Uses
Diethyltoluamide is an insect repellent especially effective against mosquitoes. O- and p-isomers are highly repellent but less effective than m-isomer.

Registry Numbers and Inventories.
CAS
134-62-3
EC (EINECS/ELINCS)
205-149-7
EC Index Number
616-018-00-2
EC Class
Harmful; Irritant; Dangerous for the Environment
R 22 36/38 52/53
RTECS
XS3675000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Human Data; Primary Irritant
Merck
13,2876
Beilstein/Gmelin
2046711
Beilstein Reference
4-09-00-01716
EPA OPP
80301
Swiss Giftliste 1
G-2482
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C12H17NO
Formula mass
191.28
Melting point, °C
-45
Boiling point, °C
298
Vapor pressure, mmHg
0.0014 (25 C)
Vapor density (air=1)
6.7
Density
0.996 g/cm3 (20 C)
Solubility in water
Slightly soluble
Refractive index
1.5205 (20 C)
Partition coefficient, pKow
2.02
Heat of vaporization
53.7 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Do not ingest or inhale. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong reducing agents, strong acids, strong bases, alkalis.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
140
Autoignition, °C
460
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Extinguishing media: Use extinguishing media most appropriate for the surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
This chemical is combustible.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Prolonged or repeated exposure may cause adverse reproductive effects. Laboratory experiments have resulted in mutagenic effects. Chronic overexposure may produce erythremia, bullous eruptions, contact urticaria, muscle cramping, slurred speech, tremors, seizures, or coma.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May cause central nervous system effects.
   Inhalation
May cause respiratory tract irritation. May cause irritation of the mucous membranes.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. Get medical aid. DO NOT use mouth-to-mouth respiration. Administer oxygen. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2924 29 95