Nabumetone

  • BRL-147777
  • 4-(6-Methoxy-2-naphthalenyl)-2-butanone
  • 4-(6-Methoxy-2-naphthyl)-2-butanone
  • 2-Butanone, 4-(6-methoxy-2-naphthalenyl)
Formula
C15H16O2
Structure

Registry Numbers and Inventories.
CAS
42924-53-8
RTECS
EL9085000
Merck
12,6428
Beilstein/Gmelin
2103472

Properties.
Formula
C15H16O2
Formula mass
228.29
Melting point, °C
80 - 81
Boiling point, °C
371
Vapor pressure, mmHg
1.1E-5 (25 C)
Density
1.084 g/cm3 (20 C)
Solubility in water
Insoluble
Partition coefficient, pKow
2.82
Heat of vaporization
61.8 kJ/mol

Hazards and Protection.
Small spills/leaks
Spread an inert absorbent on the spill and place in a suitable, properly labeled container for recovery or disposal.

Fire.
Flash Point,°C
165
Fire fighting
Water, dry powder or foam extinguishers are recommended. Carbon dioxide extinguishers may be ineffective. self contained breathing apparatus and full protective equipment are recommended for firefighters. If possible, contain and collect firefighting water for later disposal.
Combustion products
Toxic, corrosive or flammable thermal decomposition products are expected when the product is exposed to fire.

Health.
Exposure effects
Exposure might occur via skin; eyes; ingestion. Caution - Pharmaceutical agent. Possible effects of overexposure in the workplace include: irritation; coughing; increased mucous secretion; headache; nausea; dizziness; sedation. Health effects information is based on hazards of components.

First aid
 
   Ingestion
Never attempt to induce vomiting. Do not attempt to give any solid or liquid by mouth if the exposed subject is unconscious or semi-conscious. Wash out the mouth with water. If the exposed subject is fully conscious, give plenty of water to drink. Obtain medical attention.
   Inhalation
Physical form suggests that risk of inhalation exposure is negligible.
   Skin
Using appropriate personal protective equipment, remove contaminated clothing and flush exposed area with large amounts of water. Obtain medical attention if skin reaction occurs, which may be immediate or delayed.
   Eyes
Wash immediately with clean and gently flowing water. Continue for at least 15 minutes. Obtain medical attention.

Transport.