- Cyclobutylmethyldihydromorphine A
Odorless, white powder.
Opiod agonist/antagonist analgesic.
Registry Numbers and Inventories.
Melting point, °C
227 - 232
Vapor pressure, mmHg
1.1E-13 (25 C)
1.44 g/cm3 (20 C)
Solubility in water
Partition coefficient, pKow
Hazards and Protection.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect from physical damage and direct sunlight.
Wear protective gloves and clean body-covering clothing. Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container.
Stable under ordinary conditions of use and storage.
Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Extinguish with water spray, dry chemical, alcohol foam, or carbon dioxide.
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Produces acute withdrawal symptoms in individuals physically dependent on opiods. Persons with impaired kidney or liver function may be more susceptible to the effects of the substance.
Narcotic antagonist. Although not considered highly toxic, the acute toxic syndrome in non-opiod dependent subjects is not well defined. May produce constricted pupils. Large doses may cause liver damage.
Inhalation of dust may cause irritation to the respiratory tract.
Not expected to cause any adverse health effects.
No adverse effects expected but dust may cause mechanical irritation.
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Remove to fresh air. Get medical attention for any breathing difficulty.
Wash exposed area with soap and water. Get medical advice if irritation develops.
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.