Naphthylthiourea

  • ANTU
  • N-(1-Naphthyl)-2-thiourea
  • 1-Naphtylthiourea
Formula
C11H10N2S
Structure
Description
A crystalline solid or a solid dissolved in a liquid.
Uses
Antu has been found to be useful primarily for control of the norway rat. (Former use) it is not recommended for use against black rats or house mice, and is ineffective against all species of field rodents animals tend to become resistant

Registry Numbers and Inventories.
CAS
86-88-4
EC (EINECS/ELINCS)
201-706-3
EC Index Number
006-008-00-0
EC Class
Very toxic; Carcinogenic Category 3
R 28 40
S 28 36/37 45
RTECS
YT9275000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Human Data
UN (DOT)
1651
Merck
13,729
Beilstein/Gmelin
778118
Beilstein Reference
4-12-00-03086
RCRA
P072
EPA OPP
4501
Swiss Giftliste 1
G-1141
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C11H10N2S
Formula mass
202.28
Melting point, °C
204 - 205
Boiling point, °C
360
Vapor density (air=1)
6.99
Density
>1 g/cm3
Solubility in water
Insoluble
Partition coefficient, pKow
1.66

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Fire potential
May burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV (as TWA): ppm; 0.3 mg/m3 (ACGIH 1991-1992). OSHA PEL: TWA 0.3 mg/m3 NIOSH REL: TWA 0.3 mg/m3 NIOSH IDLH: 100 mg/m3
Poison_Class
1*
Exposure effects
May cause liver and kidney damage. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. Effects may be delayed.
   Ingestion
May be fatal if swallowed. May cause irritation of the digestive tract. May cause liver and kidney damage. May cause cardiac disturbances. May cause methemoglobinemia, cyanosis, convulsions, and death. May cause central nervous system effects. May cause blood abnormalities.
   Inhalation
May cause respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. May cause liver and kidney damage. Central nervous system effects may include confusion, ataxia, vertigo, tinnitus, weakness, disorientation, lethargy, drowsiness, and finally coma. May cause blood changes. May cause cardiac abnormalities.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1651
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
NTU
 
Std. Transport #
4921783