Nicergoline

  • Vasospan
  • 1,6-Dimethyl-8b-(5-bromonicotinoyloxymethyl)-10a-methoxyergoline
Formula
C24H26BrN3O3
Structure
Uses
Cerebral and peripheral vasodilator

Registry Numbers and Inventories.
CAS
27848-84-6
EC (EINECS/ELINCS)
248-694-6
RTECS
KE6341000
RTECS class
Drug; Reproductive Effector
Merck
12,6580
Beilstein/Gmelin
4828393
Beilstein Reference
6-23
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C24H26BrN3O3
Formula mass
484.39
Vapor pressure, mmHg
4E-14 (25 C)
Solubility in water
Insoluble
pKa/pKb
6.22 (pKb)
Heat of vaporization
88.6 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
313
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful. Harmful if swallowed.
   Ingestion
Harmful if swallowed.
   Inhalation
May be harmful if inhaled.
   Skin
May be harmful if absorbed through the skin.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.