- bis(Dibutyldithiocarbamate) nickel
- Nickel dibutyldithiocarbamate
- Nickel(II) dibutyldithiocarbamate
Dark green flakes with an amine-like odor.
Accelerator for rubber vulcanization.
Registry Numbers and Inventories.
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
1.26 g/cm3 (20 C)
Solubility in water
Hazards and Protection.
Stool in a cool, dry location. Keep containers closed to prevent contamination.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Not normally required. If needed, use NIOSH/MSHA approved dust respirator.
Wear protective equipment. Sweep up and place in container for disposal.
Stable at normal temperatures and pressures.
Strong oxidizing agents.
Oxides of carbon, sulfur and nitrogen.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Toxic gases and vapors (such as nickel carbonyl) may be released in a fire involving nickel.
IDHL: NIOSH considers nickel metal and other compounds (as Ni) to be a potential
G-A4, I-1, N-1, CP65
Acute intoxication of nickel carbonyl has two stages, immediate and delayed. A person may have a temperature as a delayed symptom, but it will seldom elevate above 101 degrees. Early symptoms after inhalation are dizziness, giddiness, and weakness. Nickel salts are reported to be animal teratogens. Increased incidence of stillbirth and neonatal mortality of rat offspring were associated with maternal consumption of nickel chloride solutions prior to mating and during gestation. Nickel has been found in breast milk. ORAL ADMINISTRATION of nickel sulphate to rats caused decreased testicular, prostate, and seminal vesicle size as well as abnormalities of sperm and decreased sperm count.
Large doses taken orally may cause nausea, vomiting, and diarrhea.
Nausea, vomiting, and diarrhea.
Nickel contact dermatitis is the most common reaction to nickel. It is estimated that 5 percent of all eczemas are nickel reactions. Nickel itch may begin with a burning and itching sensation, followed by erythema and nodular eruptions. Once acquired, nickel sensitivity usually persists.
Acute toxicity from nickel inhalation includes sore throat and hoarseness. There is speculation inflammation of the eye and epiphora have occurred in nickel plating work environments due to poor ventilation. Occasional exposure to nickel aerosol and other contaminants has resulted in nasal irritation, loss of smell, damage to the nasal mucosa, and perforation of the nasal septum. In rare cases, nickel workers have complained of a bitter metallic taste.
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
Move the patient to fresh air. The first phase of nickel carbonyl inhalation is deceptive in its lack of severe symptoms. Chelating agents - although penicillamine has an effect, diethyldithiocarbamate (ddc) is the preferred chelating agent in the literature. Collect an 8 hour sample immediately after exposure. Levels of: less than 10 mcg/dl: delayed symptoms are not expected. Ddc is unnecessary.
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.