Nifenazone

  • Nicotinoylantipyrine
  • N-Antipyrinylnicotinamide
  • N-Nicotinoylaminoantipyrine
  • 4-(Nicotinoylamino)antipyrine
  • 1,5-Dimethyl-4-nicotinamido-2-phenyl-3-pyrazolone
  • 4-Nicotinamido-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
Formula
C17H16N4O2
Structure
Uses
An analgesic and antipyretic.

Registry Numbers and Inventories.
CAS
2139-47-1
EC (EINECS/ELINCS)
218-387-1
RTECS
QS4005000
RTECS class
Drug
Merck
12,6619
Beilstein/Gmelin
307504
Beilstein Reference
5-25-14-00153
Japan ENCS (MITI)
Listed

Properties.
Formula
C17H16N4O2
Formula mass
308.34
Melting point, °C
256 - 258
Solubility in water
Slightly soluble
pKa/pKb
10.08 (pKb)

Hazards and Protection.
Storage
Store at 2-8 C.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Avoid contact and inhalation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.