Nitroglycerin, solution in alcohol, with more than 1% but not more than 5% Nitroglycerin

  • 1,2,3-Propanetriol, trinitrate
  • Nitroglycerol
  • Nitrocardin
  • Glyceryl trinitrate
  • Glycerin trinitrate
Formula
C3H5N3O9
Structure
Uses
Explosive. Medication

Registry Numbers and Inventories.
CAS
55-63-0
EC (EINECS/ELINCS)
200-240-8
EC Index Number
603-034-00-X
EC Class
Explosive; Very toxic; Danger of cumulative effects; Dangerous for the Environment
RTECS
QX2100000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
1204
Merck
12,8913
Beilstein/Gmelin
1802063
Beilstein Reference
4-01-00-02762
RCRA
P081
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H5N3O9
Viscosity
156.49 cp (0.5 C)
Heat of fusion
4.9 kJ/mol
Heat of combustion
-1552 kJ/mol

Hazards and Protection.
Storage
Store at room Ideal materials for s above 25C (77F). Do not refrigerate.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Use water spray to knock-down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Water spill: Use natural barriers or oil spill control booms to limit spill travel. Remove trapped material with suction hoses.
Stability
No data.
Incompatibilities
If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation Incompatible with the following: Heat, ozone, shock, acids.
Decomposition
Decomposes energetically above 145 C.

Fire.
Autoignition, °C
270
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use alcohol foam, dry chemical or carbon dioxide.
Fire potential
Flammable/combustible material.
Hazards
May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; Treat as an explosive. Keep material wet with water or treat as an explosive. Runoff to sewer may create fire or explosion hazard. MAY EXPLODE AND THROW FRAGMENTS 1600 meters (1 MILE) OR MORE IF FIRE REACHES CARGO.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
3
 
 
Reactivity
4
 

Health.
Exposure limit(s)
TLV: 0.05 ppm; 0.46 mg/m3 TWA (skin) (ACGIH 1994-1995). OSHA PEL: C 0.2 ppm (2 mg/m3) skin NIOSH REL: ST 0.1 mg/m3 skin NIOSH IDLH: 75 mg/m3
Exposure effects
Abnormally low blood pressure is common. Low heart rate may occur in predisposed patients; reflex rapid heart rate may occur. Death occurs secondary to circulatory collapse or respiratory failure. With therapeutic use - 1. Headache and dizziness are common, even after administration of therapeutic doses. Acute wernicke's encephalopathy from intravenous infusions may be precipitated by ethanol and propylene glycol diluents. In male rats, a dominant lethal test showed no effect on male fertility; interstitial cell tumors of rat testes were induced after nitroglycerin exposure. Results on teratogenicity in rats are conflicting.
   Ingestion
Nausea, vomiting, colicky pain, and diarrhea may occur.
   Inhalation
May cause irritation or burns.
   Skin
See Inhalation.
   Eyes
LOSS OF VISION - A transient loss of vision reportedly occurred before acute toxic effects from nitroglycerin exposure. Constriction of the pupil and corneal damage occurred after intravenous exposure.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult.
   Skin
Remove and isolate contaminated clothing and shoes. Wash skin with soap and water. Flush with running water for at least 20 minutes
   Eyes
Flush with running water for at least 20 minutes.

Transport.
UN number
1204
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
NTG
 
Std. Transport #
4910310