Nitrosodibutylamine

  • n-Butyl-n-nitroso-1-butamine
  • DBNA
  • Dibutylnitrosamine
  • Di-n-butylnitrosamine
  • N,N-di-n-butylnitrosamine
  • Ndba
Formula
C8H18N2O
Structure
Description
Yellow oil.
Uses
N-nitroso compounds are produced primarily as research chemicals and not for commercial purposes. N-nitroso compounds.

Registry Numbers and Inventories.
CAS
924-16-3
EC (EINECS/ELINCS)
213-101-1
RTECS
EJ4025000
RTECS class
Tumorigen; Mutagen; Reproductive Effector
Beilstein/Gmelin
1760378
Beilstein Reference
4-04-00-03389
RCRA
U172
Swiss Giftliste 1
G-5269
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C8H18N2O
Formula mass
158.28
Boiling point, °C
234
Density
0.8997 g/cm3 (20 C)
Solubility in water
0.12%
Surface tension
30.6 g/s2 (17 C)
Refractive index
1.4445 (20 C)
Partition coefficient, pKow
1.92

Hazards and Protection.
Storage
Aqueous solutions are stable for periods over 2 weeks in alkaline or neutral pH and room temperature. Acid solutions are slightly less stable. Store at in dark bottles since dibutylnitrosamine is light sensitive.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Dispensers of liquid detergent should be available. Protective suits (preferably disposable, one-piece and close-fitting at ankles and wrists), gloves, hair covering and overshoes. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators when working with particulates or gases. Protective clothing should be a distinctive color.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Stable @ room temperature for more than 14 days in neutral or alkaline aqueous solution in dark, slightly less stable in acidic solution; light-sensitive, esp to UV light.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Carcinogin
I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
The toxicological properties of this material have not been investigated.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Pesticides - remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Irritation - treat dermal irritation or burns with standard topical therapy
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
USCG CHRIS Code
NBA