- Dinitrogen monoxide
- Laughing gas
- Dinitrogen oxide
A colorless liquid. Shipped under refrigeration.
To oxidize organic compound at temp above 300 deg c, make nitrites from alkali metals at their boiling points, in rocket fuel formulations (with carbon disulfide), in prepn of whipped cream.
Registry Numbers and Inventories.
Tumorigen; Mutagen; Reproductive Effector; Human Data
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
Vapor density (air=1)
1.266 g/cm3 (20 C)
Solubility in water
0.0145 cp at 25C at 1 atm
1.75 g/s2 at 20 C in contact with vapor
Partition coefficient, pKow
Heat of vaporization
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Wear appropriate protective gloves, clothing and goggles. Always wear thermal protective clothing when handling refrigerated/cryogenic liquids.
Wear positive pressure self-contained breathing apparatus (SCBA).
Keep material out of water sources and sewers. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Moderate, can form explosive mixture with air reactive only under extreme conditions.
Explosions have occurred with ether-nitrous oxide mixtures. Spontaneous ignition occurs when nitrous oxide and lithium hydride or hydrazine are mixed.
Do not use water. Dangerously explosive. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Substance does not burn but will support combustion.
Some may react explosively with fuels. May ignite combustibles (wood, paper, oil, clothing, etc.). Vapors from liquefied gas are initially heavier than air and spread along ground. Runoff may create fire or explosion hazard. Containers may explode when heated. Ruptured cylinders may rocket.
TLV: 50 ppm; 90 mg/m3 as TWA (ACGIH 1991-1992). NIOSH REL: TWA 25 ppm (46 mg/m3) (TWA over the time exposed) *Note: REL for exposure to waste anesthetic gas.
Signs and symptoms of asphyxia include headache, dizziness, excitation proceeding to possible CNS depression, seizures, and death. Intracranial pressure may be elevated. SPERMATOGENESIS - Suppression of spermatogenesis was noted in male rats exposed to 20% nitrous oxide, 20% oxygen, and 60% nitrogen for up to 35 days. It took 3 to 6 days for sperm production to recover after exposure was discontinued (Kripke et al, 1976).
Vapors may cause dizziness or asphyxiation without warning.
Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite.
Seek medical assistance.
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. In case of contact with liquefied gas, thaw frosted parts with lukewarm water.
Immediately flush with running water for at least 20 minutes.
USCG CHRIS Code
Std. Transport #