Nordazepam

  • Praxadium
  • Dealkylprazepam
  • Demethyldiazepam
  • N-Descyclopropylmethylprazepam
  • 7-Chloro-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one
  • 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
Formula
C15H11ClN2O
Structure
Description
white solid
Uses
Primary metabolite of diazepam. US DEA Schedule IV.

Registry Numbers and Inventories.
CAS
1088-11-5
EC (EINECS/ELINCS)
214-123-4
RTECS
DF1750000
RTECS class
Drug; Mutagen; Reproductive Effector
Merck
12,6784
Beilstein/Gmelin
751823
Beilstein Reference
5-24-04-00291
New Zealand
Listed

Properties.
Formula
C15H11ClN2O
Formula mass
270.72
Melting point, °C
216 - 217
Boiling point, °C
453
Vapor pressure, mmHg
2E-8 (25 C)
Solubility in water
Insoluble
pKa/pKb
10.60 (pKb)
Heat of vaporization
71.2 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Flash Point,°C
228
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful. Harmful if swallowed. Possible risk of harm to the unborn child. Target organ(s): Central nervous system.
   Ingestion
Harmful if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.