n-Butyl lithium

  • Butyllithium
Formula
C4H9Li
Structure
Description
Clear, yellow solution in hexanes.
Uses
Organic synthesis.

Registry Numbers and Inventories.
CAS
109-72-8
EC (EINECS/ELINCS)
203-698-7
R 15 17 34
S 26 36/37/39 43 45
UN (DOT)
2445
Beilstein/Gmelin
1209227
Beilstein Reference
4-04-00-04419
Swiss Giftliste 1
G-8197
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H9Li
Formula mass
64.06
Melting point, °C
-34
Boiling point, °C
60
Vapor density (air=1)
>1
Density
0.765 g/cm3
Solubility in water
Reacts

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed to prevent drying out. Keep under a nitrogen blanket. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Keep away from organic halogens. Refrigerator/flammables.
Handling
Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Use only in a chemical fume hood. Store and handle protected from air. Do not use if the material has evaporated to dryness. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Use a fully encapsulating, vapor protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources and prevent all contact with spilled material. Stop leak if you can do it without risk. Cover with DRY earth, DRY sand, or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean non-sparking tools to collect material and place it into loosley covered plastic containers for later disposal. This is a generic DOT guideline. EXCEPTION: For Dithionite (Hydrosulfite/Hydrosulphite) spills, UN1384, UN1923 and UN1929, dissolve with 5 parts water and collect for proper disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Incompatible materials, ignition sources, exposure to air, contact with water, organic materials, strong oxidants, exposure to moist air or water, dehydrating agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, lithium hydroxide, butane, oxides of lithium.

Fire.
Flash Point,°C
-21
Autoignition, °C
240
Upper exp. limit, %
7.4
Lower exp. limit, %
1.2
Fire fighting
DO NOT USE WATER, carbon dioxide OR FOAM ON MATERIAL ITSELF. It may react violently with water. Smothering may not be effect.
Fire potential
Flammable/combustible material.
Hazards
May ignite on contact with moist air or moisture. May burn rapidly with flare-burning effect. May react vigorously or explosively on contact with water. May decompose explosively when heated or involved in a fire. May re-ignite after fire is extinguished.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
4
 
 
Reactivity
2
 

Health.
Poison_Class
2
Exposure effects
   Ingestion
Aspiration hazard. May cause central nervous system depression, kidney damage, and liver damage. Causes digestive tract burns with immediate pain, swelling of the throat, convulsions, and possible coma. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. May cause corrosion and permanent tissue destruction of the esophagus and digestive tract. May cause ear ringing, blurred vision, thyroid abnormalities, photophobia, coma, and seizures.
   Inhalation
high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Irritation may lead to chemical pneumonitis and pulmonary edema. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May cause effects similar to those described for ingestion.
   Skin
Contact with substance may cause severe burns.
   Eyes
Causes severe eye burns. May cause irreversible eye injury.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Possible aspiration hazard. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush with running water for at least 20 minutes.
   Eyes
In case of contact with substance, immediately flush with running water for at least 20 minutes.

Transport.
UN number
2445
Response guide
Hazard class
4.2
Packing Group
I