O,O-Dimethyldopamine

  • 3,4-Di-O-methyldopamine
  • Homoveratrylamine
  • Dopamine dimethyl ether
  • 3,4-Dimethoxybenzeneethanamine
  • 3,4-Dimethoxyphenethylamine
  • 2-(3,4-Dimethoxyphenyl)ethanamine
Formula
3,4-(CH3O)2C6H3(CH2)2NH2
Structure
Description
Yellow viscous liquid. Amine-like odor.

Registry Numbers and Inventories.
CAS
120-20-7
EC (EINECS/ELINCS)
204-376-9
EC Class
harmful, irritant
R 22 34
S 26 36/37/39 45
RTECS
SH2300000
RTECS class
Other
UN (DOT)
3267
Beilstein/Gmelin
474393
Beilstein Reference
4-13-00-02604
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C10H15NO2
Formula mass
181.24
Melting point, °C
12 - 15
Boiling point, °C
324
Vapor pressure, mmHg
0.00025 (25 C)
Vapor density (air=1)
6.25
Density
1.07 g/cm3
Solubility in water
Very soluble
Refractive index
1.546 (20 C)
pKa/pKb
4.34 (pKb)
Partition coefficient, pKow
1.20
Heat of vaporization
56.6 kJ/mol

Hazards and Protection.
Storage
Do not store in direct sunlight. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from moisture. Store protected from light. Store under an inert atmosphere.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. Handle under an inert atmosphere. Store protected from air. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Place under an inert atmosphere.
Disposal code
5
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Moisture, air.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
132
Autoignition, °C
380
Upper exp. limit, %
1.7
Lower exp. limit, %
0.1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
3267
Response guide
Hazard class
8
Packing Group
I; II; III
 
HS Code
2922 29 00