Octadecanonitrile

  • Heptadecyl cyanide
  • Octadecanenitrile
  • Stearonitrile
Formula
C18H35N
Structure
Description
Solid.
Uses
Chemical intermediate for fatty amines and derivatives.

Registry Numbers and Inventories.
CAS
638-65-3
EC (EINECS/ELINCS)
211-345-3
RTECS
WI5500000
RTECS class
Primary Irritant
UN (DOT)
2810
Beilstein/Gmelin
972464
Beilstein Reference
4-02-00-01242
Swiss Giftliste 1
G-5369
Canada DSL/NDSL
DSL
US TSCA
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C18H35N
Formula mass
265.54
Melting point, °C
39 - 40
Boiling point, °C
362
Vapor pressure, mmHg
3E-5 (25 C)
Density
0.8178 g/cm3 (41 C)
Solubility in water
Insoluble
Surface tension
27.1 g/s2 (80 C)
Refractive index
1.4405 (40 C)
Partition coefficient, pKow
8.05
Heat of vaporization
60.3 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
No data.
Incompatibilities
Strong acids, strong bases, strong oxidizing agents, strong reducing agents.
Decomposition
Carbon monoxide, oxides of nitrogen, carbon dioxide.

Fire.
Flash Point,°C
142
Fire fighting
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Dry chemical, carbon dioxide, alcohol-resistant foam or water spray.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
-
Exposure effects
Hypoventilation, elevated blood pressure, abnormally low blood pressure, and rapid heart rate may occur. Coma, seizures, amnesia, headache, tremors, CNS stimulation, paralysis, parkinsonism and additional sequelae may occur.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Hypoventilation, respiratory tract irritation, or pulmonary edema may develop.
   Skin
Dermal irritation and percutaneous absorption may occur.
   Eyes
Inflammation of the eye, prolonged dialation of the pupils, equally red rectinal veins and arteries upon funduscopic examination, nasal irritation, and throat irritation may occur.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Administer 100% oxygen - establish secure large bore iv. Prepare the cyanide antidote kit for use in symptomatic patients. Amyl nitrite ampule - inhale ampule contents for 30 seconds every minute until sodium nitrite is administered. Use a new ampule every 3 minutes. Sodium nitrite - administer iv (adult - 10 ml over 3 to 5 minutes; child - (with normal hemoglobin concentration) - 0.12 To 0.33 Ml/kg, up to 10 ml). Repeat one-half of initial sodium nitrite dose 30 minutes later if there is inadequate clinical response. Monitor blood pressure carefully. Reduce nitrite administration rate if hypotension occurs.
   Skin
See inhalation.
   Eyes
See inhalation.

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
I; II; III