Octadecanoyl chloride

  • Stearoyl chloride
Formula
C18H35ClO
Structure
Description
Clear, yellow liquid.
Uses
Prepn of substituted amines and amides, acid anhydrides, esterification of alcohols, synthesis of other organic compound

Registry Numbers and Inventories.
CAS
112-76-5
EC (EINECS/ELINCS)
204-004-5
R 34 37
S 26 36/37/39 45
RTECS
RG2162000
RTECS class
Other
UN (DOT)
3265
Beilstein/Gmelin
639784
Beilstein Reference
4-02-00-01240
Swiss Giftliste 1
G-8782
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C18H35ClO
Formula mass
302.98
Melting point, °C
164 - 167
Boiling point, °C
348
Vapor pressure, mmHg
5E-5 (25 C)
Density
0.9007 g/cm3 (25 C)
Solubility in water
Insoluble
Refractive index
1.4523 (24 C)
Partition coefficient, pKow
8.96
Heat of vaporization
59.2

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container. Keep under a nitrogen blanket. Corrosives area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
No data.
Incompatibilities
Oxidizing agents, strong bases, water, alcohols.
Decomposition
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
170
Fire fighting
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Dry chemical, carbon dioxide, alcohol-resistant foam or water spray.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
4
Exposure effects
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth.
   Skin
Causes burns.
   Eyes
Causes eye burns. Lachrymator.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Pesticides - remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Irritation - treat dermal irritation or burns with standard topical therapy
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
3265
Response guide
Hazard class
8
Packing Group
I; II; III