Ofloxacine

  • Tarivid
  • HOE-280
  • Oflocet
  • 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
  • 9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
  • 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10- (4-methyl-1-piperazinyl)-7-oxo-, (+-)
Formula
C18H20FN3O4

Registry Numbers and Inventories.
CAS
82419-36-1
S: 22 24/25
RTECS
UU8815500
Merck
12,6865
Beilstein/Gmelin
3657947
Korea ECL
Listed

Properties.
Formula
C18H20FN3O4
Formula mass
361.37
Melting point, °C
254 (decomposes)
Vapor pressure, mmHg
6.7E-14 (25 C)
Density
1.48 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
5.23 (pKa)
Partition coefficient, pKow
1.61

Hazards and Protection.
Storage
Keep tightly closed. Store at 2-8 C.
Protection
Protective work clothing. Chemical protective gloves. Safety glasses or goggles.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable if stored as directed..
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.

Fire.
Fire fighting
Extinguish with carbon dioxide, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Wear self-contained respirator. Wear fully protective impervious suit.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May cause irritation of the eyes, skin, mucous membranes and upper respiratory tract. May be harmful if inhaled, ingested or absorbed through the skin.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.