Ornidazole

  • (±)-Tiberal
  • 1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
  • a-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol
Formula
C7H10ClN3O3
Structure
Uses
An antiprotozoal compound for treatment of Trichomonas vaginalis infection.

Registry Numbers and Inventories.
CAS
16773-42-5
EC (EINECS/ELINCS)
240-826-0
RTECS
NI5460000
RTECS class
Drug; Mutagen; Reproductive Effector
Merck
12,7000
Beilstein/Gmelin
614299
Beilstein Reference
5-23-05-00072
Austrailia AICS
Listed
Korea ECL
Listed

Properties.
Formula
C7H10ClN3O3
Formula mass
219.63
Melting point, °C
85.4
Boiling point, °C
443
Vapor pressure, mmHg
1E-8 (25 C)
Solubility in water
Slightly soluble
pKa/pKb
11.28 (pKb)
Heat of vaporization
73.9 kJ/mol

Hazards and Protection.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Flash Point,°C
222
Fire fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful. Harmful if swallowed. Avoid contact and inhalation.
   Ingestion
Harmful if swallowed.
   Inhalation
May be harmful if inhaled.
   Skin
May be harmful if absorbed through the skin.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.