Oxaprozin

  • 4,5-Diphenyl-2-oxazolepropanoic acid
  • 4,5-Diphenyl-2-oxazolepropionic acid
  • 2-Oxazolepropanoic acid, 4,5-diphenyl
  • Durapro
  • WY 21743
  • Oxapro
Formula
C18H15NO3
Structure
Uses
Nonsteroidal anti-inflammatory drug - NSAID.

Registry Numbers and Inventories.
CAS
21256-18-8
EC (EINECS/ELINCS)
244-296-1
RTECS
RP6990000
RTECS class
Drug; Reproductive Effector; Human Data
Merck
12,7057
Beilstein/Gmelin
1083168
Beilstein Reference
6-27

Properties.
Formula
C18H15NO3
Formula mass
293.32
Melting point, °C
158 - 161
Boiling point, °C
467
Vapor pressure, mmHg
2E-9 (25 C)
Solubility in water
Insoluble
pKa/pKb
4.19 (pKa)
Heat of vaporization
76.8 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Protective gloves. Chemical safety goggles.
Respirators
Wear dust mask.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
236
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
0
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May be harmful if swallowed.
   Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.