Oxytetracycline

  • Adamycin
  • Berkmycen
  • Biostat
  • Dabicycline
  • [4S-(4 alpha, 4a alpha, 5 alpha,5a alpha,6 beta,12a alpha)]-4-(dimethylamino)-1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 5, 6, 10, 12, 12a-hexahydroxy-6-methyl-1, 11-dioxo-2-naphthacenecarboxamide
Formula
C22H24N2O9
Structure
Description
Pale yellow to tan, crystalline powder.
Uses
Inhibition of lethal yellowing in coconut palm trees, bactericide.

Registry Numbers and Inventories.
CAS
79-57-2
EC (EINECS/ELINCS)
201-212-8
RTECS
QI7875000
RTECS class
Agricultural Chemical and Pesticide; Drug; Mutagen; Reproductive Effector; Human Data
Merck
12,7111
Beilstein/Gmelin
2714587
Beilstein Reference
4-14-00-02633
EPA OPP
6304
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C22H24N2O9
Formula mass
460.44
Melting point, °C
184.5 - 185.5
Vapor density (air=1)
15.9
Density
1.634 g/cm3 (20 C)
Solubility in water
0.2 g/L

Hazards and Protection.
Storage
Store in a cool, dry place. Do not store in direct sunlight. Keep from freezing. Keep container closed when not in use. Store below 40C.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Use water spray to reduce vapors or divert vapor cloud drift.
Stability
Stable under normal temperatures and pressures. Darkens and decomposes on exposure to light.
Incompatibilities
Acidic conditions, strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance is noncombustible. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May cause reproductive and fetal effects. Chronic exposure may cause blood effects.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause an anticoagulant effect in the blood.
   Inhalation
Dust is irritating to the respiratory tract. May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation and possible burns.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.