o-Chlorophenol

  • Chlorophenolate
  • 2-Chlorophenol
  • 1-Chloro-5-hydroxybenzene
Formula
C6H5ClO
Structure
Description
Colorless to yellow-brown liquid, unpleasant penetrating odor.
Uses
Organic synthesis (dyes).

Registry Numbers and Inventories.
CAS
95-57-8
EC (EINECS/ELINCS)
202-433-2
EC Index Number
604-008-00-0
EC Class
Harmful; Dangerous for the Environment
R 20/21/22 51/53
RTECS
SK2625000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector
UN (DOT)
2021
Merck
12,2173
Beilstein/Gmelin
1905114
Beilstein Reference
4-06-00-00782
RCRA
U048
EPA OPP
62204
Swiss Giftliste 1
G-1415
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H5ClO
Formula mass
128.56
Melting point, °C
75 - 76
Boiling point, °C
175
Vapor pressure, mmHg
0.88 (25 C)
Vapor density (air=1)
4.4
Saturation Concentration
2900 ppm (0.29%) at 20 C (calculated)
Odor Threshold Odor threshold 1.8E-4 mg/L
Critical temperature
441
Critical pressure
54.1
Density
1.25 g/cm3 (20 C)
Solubility in water
28.5 g/L
Viscosity
4.11 cp @ 25 C
Surface tension
42.25 g/s2 (12.7 C)
Refractive index
1.5524 (20C)
pKa/pKb
8.50 (pKa)
Partition coefficient, pKow
2.15
Heat of vaporization
42.8 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.
Disposal code
2
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
72
Autoignition, °C
550
Upper exp. limit, %
8.8
Lower exp. limit, %
1.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated. Extinguishing media: Use water spray to cool fire-exposed containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Fire potential
Moderate fire hazard when exposed to heat, flames, or oxidizers.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Toxic and irritating hydrogen chloride and chlorine gases may form in fires.
Health
2
 
Flammability
2
 
 
Reactivity
0
 

Health.
Carcinogin
I-2B
Poison_Class
3
Exposure effects
Prolonged or repeated inhalation may cause kidney and lung damage. May cause cancer according to animal studies. Repeated exposure may cause central nervous system damage.
   Ingestion
May cause severe and permanent damage to the digestive tract. May be harmful if swallowed. Causes digestive tract irritation with possible burns.
   Inhalation
Causes respiratory tract irritation with possible burns.
   Skin
Causes skin burns. May cause contact dermatitis.
   Eyes
Causes eye burns.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2021
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
CRH
 
21 Phenols, Cresols
HS Code
2908 10 00
 
IMO Pollution Category
#