o-Nitroanisole

  • 2-methoxynitrobenzene
  • 2-Nitroanisole
Formula
2-(NO2)C6H4OCH3
Structure
Description
Colorless to yellowish liquid.
Uses
Organic synthesis, intermediate for pharmaceuticals, dyes.

Registry Numbers and Inventories.
CAS
91-23-6
EC (EINECS/ELINCS)
202-052-1
EC Index Number
609-047-00-7
EC Class
Carcinogenic Category 2; Harmful
R 45 22
RTECS
BZ8790000
RTECS class
Tumorigen; Mutagen
UN (DOT)
2730
Merck
12,6682
Beilstein/Gmelin
1868032
Beilstein Reference
4-06-00-00798
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H7NO3
Formula mass
153.14
Melting point, °C
9
Boiling point, °C
273
Vapor pressure, mmHg
0.004 (25 C)
Density
1.254 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
0.838 (131 C)
Surface tension
45.0 g/s2 (25 C)
Refractive index
1.5161 (20 C)
Partition coefficient, pKow
1.73

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Provide ventilation.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents. Explosive reaction with sodium hydroxide + zinc, vigorous reaction with hydrogen + catalyst
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
142
Autoignition, °C
464
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: For large fires, use water spray, fog, or alcohol-resistant foam. For small fires, use dry chemical, carbon dioxide, halon, or water spray.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Containers may explode when heated.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OEL-RUSSIA:STEL 1 mg/m3;Skin
Carcinogin
I-2B, N-2, CP65
Exposure effects
May cause cancer in humans.
   Ingestion
May cause irritation of the digestive tract. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed.
   Inhalation
Effects may be delayed. May cause respiratory tract irritation.
   Skin
May cause skin irritation. If absorbed, causes symptoms similar to those of ingestion. Effects may be delayed.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2730
Response guide
Hazard class
6.1
Packing Group
III
 
HS Code
2909 30 90